Fathers and grandfathers of science: checklists, statin myalgia and breast cancer
This week: surgical checklists, statin myalgia and breast cancer radiotherapy
Janice, Nathan, and Amol want you to:
1. Understand the effect of surgical safety checklist implementation on surgical complication rates.
2. Understand the use of n-of-1 trials in evaluating the association between statin use and myalgia.
3. Recognize that intraoperative radiotherapy for breast cancer may be a viable alternative to standard postoperative external beam radiation therapy in terms of local recurrence.
Continuing Medical Education
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Jayant Vaidya et al. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial. Lancet. 2013; 383:603-613. (PubMed)
Other Links Discussed this Week
Judith Finegold et al. What proportion of symptomatic side effects in patients taking statins are genuinely caused by the drug? Systematic review of randomized placebo-controlled trials to aid individual patient choice, Eur J Prev Cardiol, 2014 Apr;21(4):464-74.
Question of the Week
Is it the surgical checklist or safety culture that matters to reduce surgical complication rates?