Yin and Yang: Aspirin and Surgical Risk and Blood Transfusions and Risk of Infection
This week: Perioperative Aspirin and Blood Transfusions and Hospital-acquired Infections
Nathan and Amol want you to:
1. Understand that the use of perioperative ASA did not reduce the rate of postoperative MI or death, but was found to increase the rate of major bleeding.
2. Recognize that it may be difficult to generalize the findings of the POISE-2 trial to the bedside given the heterogeneity among the patients studied and operations performed.
3. Recognize that blood transfusion may be associated with an increased risk of all hospital-acquired infections (not just blood-borne infections) but the evidence is still preliminary.
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