Close to My Heart: Aspirin for Preterm Preeclampsia and Natriuretic Guided Therapy for Heart Failure


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This week on The Rounds Table Kieran Quinn and Fraser Pollard cover two new studies; the first investigates medical treatment to reduce the risk of preterm pre-eclampsia, and the second examines natriuretic peptide guided therapy for management of heart failure with reduced ejection fraction. Sheliza Halani and Emily Hughes round out the episode with a special segment on pharmacological treatment of heart failure.

Preterm preeclampsia is an important cause of maternal and perinatal death and complications. Fraser covers a multicenter, double-blind, placebo controlled trial which examines the effect of low dose aspirin during pregnancy on the risk of developing preterm preeclampsia.

Next, did you know that heart failure remains the number one reason for admission and readmission to hospital and has extremely high mortality rates? In a special segment, Sheliza and Emily cover five key things to know about the pharmacological treatment of the condition.

Kieran carries on the theme of heart failure management through covering a trial which examines the effect of natriuretic peptide guided therapy on hospitalization or cardiovascular mortality in patients with heart failure with reduced ejection fraction.

Finally, it wouldn’t be The Rounds Table without the Good Stuff segment! Kieran covers a new initiative that reunites transplant patients with their former organs for education and therapy. Fraser covers lice treatment: who knew that it has become increasingly difficult to treat infestation?

Like what you hear? Rate us on iTunes! Chat with us on Twitter @roundstable and tweet at Kieran directly @kieranlquinn, Sheliza @sheliza_halani, and Emily @emmy_hughes

The Papers

1. ASA in Pregnancy: http://www.nejm.org/doi/full/10.1056/NEJMoa1704559

2. BNP and HFrEF: http://jamanetwork.com/journals/jama/article-abstract/2649188

5 Things to Know About Heart Failure

  1. https://www.ncbi.nlm.nih.gov/pubmed/21641346
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538984/
  3. http://circ.ahajournals.org/content/early/2013/06/03/CIR.0b013e31829e8776
  4. https://academic.oup.com/eurheartj/article/33/14/1787/526884/ESC-Guidelines-for-the-diagnosis-and-treatment-of
  5. https://www.ccs.ca/images/Guidelines/Companion_Resources/CCS_Guidelines_eng.pdf
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1861501/#ref2

Good Stuff

1. Close to My Heart: https://www.theatlantic.com/health/archive/2017/08/heart-to-heart-transplants-therapy/537504/?utm_source=feed

2. Revenge of the Super Lice: https://www.scientificamerican.com/article/revenge-of-the-super-lice/

Music Credits

The Rounds Table Theme Music by Brendan Quinn, Creative Director and Composer, Vapor RMW

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