Sorry Sports Analogies: Statins in ARDS and COPD, Rotavirus Vaccine
This week: Statins for COPD, ARDS and human-bovine Rotavirus vaccine
Fahad and Amol want you to:
1. Understand that 2 high quality RCTs demonstrate that statins are not effective in improving clinical outcomes in either COPD or Acute Respiratory Distress Syndrome (ARDS).
2. Recognize that a novel Rotavirus vaccine was developed through an international public-private partnership that is safe, effective, and affordable for low income countries.
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National, Heart, Lung and Blood Institute ARDS Clinical Trials Network, Truwit JD, Bernard GR et al. Rouvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med 2014; 370(23):2191-2200. (PubMed).
Bhandari N, Rongsen-Chandola T, Bavdekar A, et al. Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial. Lancet 2014; Jun 21; 383(9935):2136-43. (PubMed).
Other articles mentioned: