Brain Week: Early Rehab for Stroke and Drug Interaction Increases Bleeding in Brain


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Amol, general internal resident at the University of Toronto, and Raed Joundi, neurology resident at the University of Toronto, discuss 2 recent studies:

Is early mobilization helpful for stroke patients? A randomized control trial showed that early aggressive rehabilitation for acute stroke patients resulted in worse outcomes. Amol and Raed speculate reasons behind this counter-intuitive finding.

A study that analyzed administrative data from insurance claims in Korea found that patients who received both anti-depressants and anti-inflammatory medications have an increased risk for intracranial hemorrhage. Should drug interaction results from massive registries be used to dictate prescribing practices?

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The papers

1. Early rehabilitation for stroke patients: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)60690-0/fulltext?rss=yes

2. Drug interaction that increase intracranial hemorrhage: http://www.bmj.com/content/351/bmj.h3517

Good Stuff

Music Credits (Creative Commons)

In your Robotic Heart – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/in-your-robotic-heart

Drive – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/drive-fresh-upbeat-pop-background-music

Swingin’ Jazz – Nicolai Heidlas ‎https://m.soundcloud.com/nicolai-heidlas/jazz-blues-background-music

All tracks have been modified for the purposes of this podcast.

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