Cracking Down: E-Cigarettes for Smoking Cessation and Medication for Opioid Use Disorders after Nonfatal Opioid Overdose

Paxton Bach, general internist in Vancouver, is hosting this week’s episode of The Rounds Table alongside Kate Colizza generalist internist in Calgary.  This week they are covering studies related to addiction medicine that are relevant to all areas of practice – the use of e-cigarettes for smoking cessation and initiation of medication for opioid use

Pregnancy & Prescription Pads: Maternal Ondansetron Use, Renal Function in Pregnancy and Assessing Prescribing and Deprescribing Patterns

Kieran Quinn is back on the Rounds Table this week with Michael Fralick, general internist at the University of Toronto. This week they are covering four articles in rapid-fire style on maternal first trimester ondansetron and fetal outcomes, assessment of outpatient antibiotic prescribing patterns, creatinine in the peri-partum period, and a pharmacist-led intervention for deprescribing. The

Superbugs Going Superbad: Ceftazidime-Avibactam Salvage Therapy for Klebsiella pneumoniae and Transcatheter Mitral-Valve Repair in Heart Failure

Andre Madison, General Internal Medicine (GIM) fellow at Western University, is back on The Rounds Table with Michael Juba, clinical pharmacist at London Health Sciences Centre in Infectious Disease and Anti-Microbial Stewardship.  Together they are covering the efficacy of ceftazidime-avibactam salvage therapy for Klebsialla pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae and transcatheter mitral-valve repair in heart

An Ounce of Prevention: Pantoprazole in the Intensive Care Unit and Aspirin for Primary Prevention in Diabetes

Christopher Giuliano, clinical pharmacist, is hosting this week’s episode of The Rounds Table with Claudia Hanni, an Internal Medicine clinical pharmacist.  Together they are covering pantoprazole for gastrointestinal bleeding in the intensive care unit and aspirin for primary prevention in patients with diabetes. In the intensive care unit, many patients receive pantoprazole for prevention of

Mind Over Matter: Antipsychotics for Intensive Care Unit-Associated Delirium and Fluoxetine after Acute Stroke

Jonathan Gravel, family medicine resident at the University of Toronto, is joined by Matthew Jefkins, internal medicine resident at Queen’s University, on this week’s episode of The Rounds Table. Together they are covering the use of haloperidol and ziprasidone for delirium in critical illness and fluoxetine on functional outcomes after acute stroke (FOCUS trial). Delirium affects

Quit Buggin’ Me: Antibiotic Prophylaxis for Infective Endocarditis and Baloxavir Marboxil for Uncomplicated Influenza

Andre Maddison, General Internal Medicine (GIM) fellow at Western University, is hosting this week’s episode on The Rounds Table alongside Mike Nicholson, clinical fellow in cystic fibrosis at the University of Toronto. Together they are covering antibiotic prophylaxis and incidence of infective endocarditis and baloxavir marboxil for uncomplicated influenza. Influenza viruses are emerging resistance to

TRED-ing on Thin Ice: Withdrawal of Therapy in Recovered Cardiomyopathy and Icosapent Ethyl for Hypertriglyceridemia

Paxton Bach and Samantha Young, both general internists in Vancouver are back on The Rounds Table!  Together they are covering the withdrawal of heart failure treatments in patients with recovered dilated cardiomyopathy and icosapent ethyl for cardiovascular risk reduction in patients with hypertriglyceridemia. There is good evidence behind our guidelines for the management of heart

Are Your Vitamins Vital? Cardiorespiratory Fitness on Mortality and Vitamin Supplementation for Prevention of Cancer and Cardiovascular Disease

Katie Wiskar, fellow in General Internal Medicine at the University of British Columbia, and Kate Shoults, general internist in the Greater Vancouver Area, are joining us on The Rounds Table this week!  They are covering the association between cardiorespiratory fitness and long-term mortality, and vitamin D and omega-3 fatty acids and the prevention of cancer

Salty or Sweet: ARNIs, Reduced Salt Intake in HF, and Cardiovascular Safety of Diabetes Medications

Michael Fralick and John Fralick, both general internists in Toronto, kick off The Rounds Table for the New Year.  They cover four articles in a rapid-fire style, including: angiotensin receptor-neprilysin inhibitors (ARNIs) in decompensated heart failure (HF), linagliptin and major cardiovascular events, reduced dietary salt intake in heart failure, and dapagliflozin and cardiovascular outcomes. Sacubitril/valsartan

REPLAY: Bugs & Guts – Carbapenem-Sparing Agents in Resistant Infections and Omeprazole in Coronary Artery Disease

Kieran Quinn is joined by Kevin Venus, fellow in General Internal Medicine at the University of Toronto, on this week’s episode of The Rounds Table.  Together they cover the use of a carbapenem versus a carbapenem-sparing agent in resistant bacteremias and the efficacy of proton-pump inhibitors (PPIs) in preventing gastrointestinal bleeding when using anti-thrombotic therapy

The Clot Thickens: Outpatient Management of ED Patients with Pulmonary Embolism & NSAIDs and OACs in Atrial Fibrillation

Jonathan Gravel and Peter Reardon host this week’s episode of The Rounds Table. Together they cover outpatient management of Emergency Department (ED) patients with pulmonary embolism and combining NSAIDs and oral anticoagulants in patients with atrial fibrillation. Peter shares a post-hoc analysis of NSAIDs in the RE-LY (Randomized Evaluation of Long Term Anticoagulant Therapy) trial

The Polar Express: Sustained Hypothermia for Severe TBI & Low-Dose Theophylline for COPD

Freddy Frost and Alex Pickard return to The Rounds Table this week. Together they cover the use of sustained prophylactic hypothermia in the management of traumatic brain injury (TBI) and the effectiveness of adding low-dose theophylline to inhaled corticosteroids in chronic obstructive pulmonary disease (COPD). TBI is a leading cause of death and disability, especially

Bugs & Guts: Carbapenem-Sparing Agents in Resistant Infections and Omeprazole in Coronary Artery Disease

Kieran Quinn is joined by Kevin Venus, fellow in General Internal Medicine at the University of Toronto, on this week’s episode of The Rounds Table.  Together they cover the use of a carbapenem versus a carbapenem-sparing agent in resistant bacteremias and the efficacy of proton-pump inhibitors (PPIs) in preventing gastrointestinal bleeding when using anti-thrombotic therapy

Believe It or Clot: Rivaroxaban in Preventing Thrombosis in Anti-Phospholipid Syndrome and in Cancer

Christopher Guiliano, clinical pharmacist, is back on The Rounds Table with Carrie Hartner, clinical pharmacist in the medical intensive care unit.  Together they cover rivaroxaban in preventing thrombosis in patients with Anti-phospholipid syndrome (APS) and in patients with cancer. The prevalence of APS is 50 in 100,000 patients and it is associated with arterial and

Sunsets & Heartbeats: Therapy De-Escalation in COPD and Post-Operative Atrial Fibrillation

Kieran Quinn is back with Daniel Marinescu, fellow in Respirology at the University of Toronto.  Together they cover the SUNSET trial on long-term triple therapy de-escalation in patients with chronic obstructive pulmonary disease (COPD) and the risk of thromboembolism associated with post-operative atrial fibrillation. The new Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines

REPLAY: Cut & Dried – Malignant Pleural Effusions and Tranexamic Acid in Intracerebral Haemorrhage

Freddy Frost, research fellow in cystic fibrosis in Liverpool, hosts this week’s episode of The Rounds Table with Alex Pickard, trainee in acute and emergency medicine in South London.  Together they cover new research on draining malignant pleural effusions and tranexamic acid in intracerebral haemorrhage. To start, Freddy walks listeners through a multicenter study looking