research

The surprising science behind evidence-based hospital design

Rahel Yetbarek sits with her feet up, looking out onto the city and the large swath of treed land that surrounds the freeway below her. The nurse is taking in the view over her lunch break, from the 10th floor rooftop garden at Bridgepoint, a Toronto hospital. Nearby, a few patients do the same. The

Should patients be told about incidental findings from genetic testing?

Genetic testing

Genomics is moving at a lightning pace. Whole genome sequencing, a special type of genetic test, can produce much more information about a person’s genes than ever before. However, this rapid advance in technology has outpaced our ability to understand what to do with all of this additional information. As a result, patients and clinicians

Health service researchers – are we blind to our own conflicts of interest?

Andreas Laupacis healthydebate editor

Ritika Goel’s recent commentary on Healthy Debate about the pharmaceutical industry’s influence on physicians got me thinking about other kinds of conflict of interest within the health care system, particularly related to health services researchers. There is a great need for researchers to be independent when conducting their work, and to be able to speak

Groundbreaking Canadian cohort studies aim to shed light on risk factors for cancer, chronic diseases

Groundbreaking Canadian cohort studies aim to shed light on risk factors for cancer, chronic diseases

The British Whitehall studies helped establish the importance of the social determinants of health, while a Danish study of children provided strong evidence to disprove the damaging MMR-vaccine-causes-autism hypothesis. Those are just two of many international cohort studies—studies that follow large groups of people over many years. In Canada, starting such studies has never been

Cancer research: should investments reflect disease burden?

Cancer research: should investments reflect disease burden?

Vigorous patient advocacy over the past 25 years has pushed funding for breast cancer research in Canada to the top of the charts, outstripping the amounts devoted to research into other cancers. It’s a remarkable success story for a type of cancer that, just forty years ago, was spoken of only in hushed tones. But

Patient-oriented research in Canada: what progress has been made?

PCORI, SPOR, Patient oriented research

The governments of Canada and the United States have patient-oriented research initiatives underway, which share the goals of supporting research that will improve health care systems and directly benefit patients.  However, the mandate, structure and funding of these initiatives differ significantly, with the United States accomplishing a great deal in a relatively short period of

It is time to support the pharmaceutical industry

Doug Coyle Pharmaceutical Industry Drug Costs

When I present my research, a question I often get asked is “When will Canada support the pharmaceutical industry?”  What do they mean? With sales of $41.3 billion in 2009 and net revenues of $1.3 billion, the industry would in all accounts appear healthy. Furthermore, employment in the pharmaceutical industry has increased by 12% in

Opinions, biases and conflicts of interest

Andreas Laupacis healthydebate editor

A recent article in a scientific journal has stimulated an interesting debate about the make up of advisory boards in health care, and what constitutes a conflict of interest. Dr. Barry Rubin is a vascular surgeon in Toronto and a member of an Expert Panel of the Canadian Institutes of Health Research (CIHR) that is

Managing conflicts of interest in research

conflict of interest health care intellectual conflict financial conflict COI

There have been a number of recent reports of conflicts of interest in medical research. There are at least two types of conflicts of interest – financial conflicts, where researchers stand to gain financially from their work; and intellectual conflicts, where researchers stand to gain professionally. Ensuring that all conflicts of interest are declared and

The influence of politics & the public on research funding in Canada

The recent controversy about a new treatment for multiple sclerosis (MS) has raised questions about the role of patients and politicians in determining health research priorities. In the past, the scientific community has generally determined what research is conducted. However the public is increasingly demanding that they be involved in setting research priorities – the