Amol and Janice want you to understand the following:
1. Several RCTs and observational studies suggest that Transcatheter Aortic Valve Replacement reduces mortality and improves symptoms in frail, elderly patients.
2. A historical analysis demonstrates that the sugar industry had heavy influence in setting national dental research priorities in the 1970s, which is relevant for industry relations in research today.
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SR Kapadia et al. 5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial. Lancet. 2015 Mar 15. pii: S0140-6736(15)60290-2. Epub. (PubMed).
CE Kearns et al. Sugar industry influence on the scientific agenda of the National Institute of Dental Research’s 1971 National Caries Program: a historical analysis of internal documents. PLOS Med. 2015 Mar 10;12(3):e1001798. (PubMed).