An Exercise in Contrasts: Contrast Induced Nephropathy and Exercise in Cancer

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This week, Amol discusses contrast induced nephropathy. At an overall reported incidence of 10%, contrast induced nephropathy leads to worse clinical outcomes and double the rate of mortality. A systematic review and meta-analysis on the effectiveness of prevention strategies found that there is no strong evidence for any intervention beyond volume expansion with saline. N-acetyl cysteine may have modest benefits and statins may provide benefits in patients receiving intra-arterial contrast.

We also welcome Dr. Michelle Nadler, an internal medicine resident at McMaster University. Her guest segment describes the first Canadian guidelines for clinicians on the safety and efficacy of exercise for people living with cancer.

Are you interested in contributing to the show? Contact Amol at amol.a.verma@gmail.com or Tweet us @roundstable!

The Papers

1. Risk prediction models: http://www.bmj.com/content/351/bmj.h4395

2. Prevention strategies for contrast induced nephropathy: http://annals.org/article.aspx?articleid=2484876

3. Exercise guidelines for people with cancer: https://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=342807 (short version), https://www.cancercare.on.ca/common/pages/UserFile.aspx?fileId=342805 (long version)

Two Truths, One Lie

1. http://www.cdc.gov/handwashing/show-me-the-science-handwashing.html

2. http://www.caregivingmatters.ca/what-you-need-to-know-about-hospital-acquired-infections/

3. http://www.cdc.gov/healthywater/hygiene/fast_facts.html

Good Stuff

1. Effect of avoidance on peanut allergy: http://www.nejm.org/doi/full/10.1056/nejmoa1514209

Music Credits (Creative Commons)

In your Robotic Heart – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/in-your-robotic-heart

Drive – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/drive-fresh-upbeat-pop-background-music

Vintage Dream – Nicolai Heidlas https://soundcloud.com/nicolai-heidlas/vintage-dream-loungejazzy-background-music

All tracks have been modified for the purposes of this podcast.

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