Episode 14 – Rapid Fire SARS-CoV-2 Vaccines

Welcome back Rounds Table Listeners!

This week we are going back to our Rapid Fire Format to review two papers looking at potential SARS-CoV-2 vaccines.

  1. What is the safety profile and immune system response for a novel SARS-CoV-2 specific vaccine? https://www.nejm.org/doi/full/10.1056/NEJMoa2022483 (1:05-8:44)
  2. What is the safety, reactogenicity, and immunogenicity of a viral vectored coronavirus vaccine that expresses the spike protein of SARS-CoV-2? https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext (8:45-20:31)

And for the Good Stuff:

  1. No further description needed, just a guy painting a portrait of himself, painting a portrait of himself, on repeat: https://digg.com/2020/guy-paints-himself-painting-himself-over-and-over
  2. A nice review on why we should drink coffee from NEJM: https://www.nejm.org/doi/full/10.1056/NEJMra1816604

Questions? Comments? Feedback? We’d love to hear from you. @roundstable

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1 Comment
  • Richard Fralick says:

    A short review on immunology, a reminder about the ‘lasting’ effect from the CD4 T cell response to an immunization, and an informative review of two vaccine studies, notably the one from the Oxford group. Thanks so much!


Michael Fralick

Co-director of the Rounds Table

Michael Fralick is a general internist at Mount Sinai Hospital in Toronto. He completed a Master of Science in Clinical Epidemiology at Harvard University, including a Research Fellowship in Health Policy at the Program On Regulation Therapeutics and Law (PORTAL). His PhD focused on the intersection between machine learning and pharmacoepidemiology.

John Fralick


John Fralick is a general internist at Foothills Medical Centre in Calgary. He completed a Master of Science in Epidemiology at Queen’s University. He completed medical school at the University of Calgary and did his internal medicine training at the University of Toronto.