The CHIPS trial of Hypertension in Pregnancy and TIPPS trial of Thrombophilia in Pregnancy
Janice and Amol want you to understand the following:
1. Tight blood pressure control in pregnancy does not affect fetal outcomes in pregnancy compared with loose blood pressure control. The only difference in maternal outcomes is a reduced risk of severe hypertension in the tight blood pressure control group.
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MA Rodger et al. Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial. Lancet. 2014 Nov 8;384(9955):1673-83. (PubMed).