Dropping Names and Dropping Weight: The obesity paradox and new cholesterol guidelines

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This week: Cardiovascular Disease and Population Health

Fahad and Amol want you to:

1. Understand that high quality evidence now demonstrates that obesity does not confer a survival benefit in Type 2 Diabetes, and patients should aim to achieve a normal body weight.

2. Recognize that the new cholesterol guidelines move away from specific lipid targets and recommend statin therapy for an increased number of adult patients.

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The papers

Deirdre K. Tobias et al. Body-Mass Index and Mortality among Adults with Incident Type 2 Diabetes. N Engl J Med 2014; 370:233-244

Michael J. Pencina et al. Application of New Cholesterol Guidelines to a Population-Based Sample. N Engl J Med 2014; 370:1422-1431

Additional articles mentioned:

Mercedes R. Carnethon et al. Association of Weight Status With Mortality in Adults With Incident Diabetes. JAMA. 2012;308(6):581-590.

Ed Silverman. The New Cholesterol Guidelines and Conflicts of Interest. Forbes.com, Nov 20, 2013.

Good stuff


India’s Particulate Problem, Michael Greenstone and Rohini Pande, New York Times, February 9, 2014.


A Day In The Life Of A Patient: Why Can’t We Do Better, Harlan Krumholz, Forbes.com, September 19, 2013. 

Reducing the Trauma of Hospitalization, Allan S. Detsky and Harlan Krumholz, JAMA, May 1, 2014. 

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