Rapid Fire: Respirology (And welcome back Drs. Kieran Quinn and Emily Hughes!)

Welcome back Rounds Table Listeners!

For episode 5 we have two very special guests co-hosting.

Welcome back to Drs. Kieran Quinn and Emily Hughes. This episode they discuss 4 articles on all things Respirology.

Classic rapid fire format, let’s dive right in.

  1. Can the β-blocker, metoprolol, be used to prevent COPD exacerbations? (00:00 to 06:48) (https://www.nejm.org/doi/full/10.1056/NEJMoa1908142)
  2. What is the safety and efficacy of the monoclonal antibody, benralizumab – an IL5 inhibitor, in preventing COPD exacerbations? (06:49 to 10:12) (https://www.nejm.org/doi/full/10.1056/NEJMoa1905248)
  3. A new antibiotic for community acquired pneumonia: is treatment with oral lefamulin non-inferior to moxifloxacin? (10:20 to 16:22) (https://jamanetwork.com/journals/jama/article-abstract/2752331)
  4. What are the predictors and outcomes associated with excess duration of antibiotic treatment in patients hospitalized with pneumonia? (16:25 to 21:44)https://annals.org/aim/article-abstract/2737823/excess-antibiotic-treatment-duration-adverse-events-patients-hospitalized-pneumonia-multihospital

Last but not least, the Good Stuff:

  1. What you should know about severe lung illness related to vaping:


  1. A meta-analysis metastasis; metanalysis are taking over medical literature:



Questions? Comments? Feedback? We’d love to hear from you. @roundstable

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Michael Fralick

Co-director of the Rounds Table

Michael Fralick is a general internist at Mount Sinai Hospital in Toronto. He completed a Master of Science in Clinical Epidemiology at Harvard University, including a Research Fellowship in Health Policy at the Program On Regulation Therapeutics and Law (PORTAL). His PhD focused on the intersection between machine learning and pharmacoepidemiology.

John Fralick


John Fralick is a general internist at Foothills Medical Centre in Calgary. He completed a Master of Science in Epidemiology at Queen’s University. He completed medical school at the University of Calgary and did his internal medicine training at the University of Toronto.

Kieran Quinn


Kieran is a clinical scientist at the Sinai Health System.

Emily Hughes


Emily is an Internal Medicine Resident at the University of Toronto Department of Medicine.

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