100% Bullish: Simvastatin in MS, Communicating Risk

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Originally Aired September 10, 2014: Simvastatin in Secondary Progressive Multiple Sclerosis and Communicating With Patients About Risk

Rebecca and Amol want you to:

1. Recognize that simvastatin reduces the rate of whole brain atrophy in secondary progressive MS, which may be a promising new use for statins.

2. Understand that effective strategies to communicate risk include: Using visual aids, speaking in terms of absolute risk, and using quantitative descriptors whenever possible.

Continuing Medical Education

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The papers

J Chataway et al. Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial. Lancet. 2014 Jun 28;383(9936):2213-21. (PubMed). 

D Zipkin et al. Evidence-Based Risk CommunicationA Systematic Review. Ann Intern Med. 2014 Aug 19;161(4):270-80. (PubMed). 

Good stuff


How to Get Through a Work Day on no Sleep, Melissa Dahl, New York Magazine. August 13, 2014. 


Why toxic algae blooms are taking over Lake Erie – again.  Vox.com. August 4, 2014.

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