Summer Replay 3: Transcatheter Aortic Valve Replacements and Sugar Industry Influence on Research Priorities

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Originally aired May 22, 2015. Amol and Janice want you to understand the following:

1. Several RCTs and observational studies suggest that Transcatheter Aortic Valve Replacement reduces mortality and improves symptoms in frail, elderly patients.

2. A historical analysis demonstrates that the sugar industry had heavy influence in setting national dental research priorities in the 1970s, which is relevant for industry relations in research today.

The papers

SR Kapadia et al. 5-year outcomes of transcatheter aortic valve replacement compared with standard treatment for patients with inoperable aortic stenosis (PARTNER 1): a randomised controlled trial. Lancet. 2015 Mar 15. pii: S0140-6736(15)60290-2. Epub. (PubMed).

CE Kearns et al. Sugar industry influence on the scientific agenda of the National Institute of Dental Research’s 1971 National Caries Program: a historical analysis of internal documents. PLOS Med. 2015 Mar 10;12(3):e1001798. (PubMed).

Good Stuff

Love, Death and Spaghetti. Theresa Brown. New York Times. 2015 Apr 11.

Nicola’s Death Star strikes back: Now visitors to £1billion Glasgow super-hospital get stuck in the lifts… because they have no buttons inside. Hannah Parry. Mail Online. 2015 May 10.

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